Folliculin Interacting Protein-1 Maintains Metabolic Homeostasis During B Cell Development by Modulating AMPK, mTORC1, and TFE3

Folliculin Interacting Protein-1 (Fnip1) is a cytoplasmic protein originally discovered through its interaction with the master metabolic sensor 5’ AMP-activated protein kinase (AMPK) and Folliculin (FLCN), a protein mutated in individuals with Birt-Hogg-Dubé Syndrome. In response to low energy, AMP...

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Publicado no:J Immunol
Main Authors: Ramίrez, Julita A., Iwata, Terri, Park, Heon, Tsang, Mark, Kang, Janella, Cui, Katy, Kwong, Winnie, James, Richard G., Baba, Masaya, Schmidt, Laura S., Iritani, Brian M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6864314/
https://ncbi.nlm.nih.gov/pubmed/31676673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900395
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