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Allosteric discrimination at the NADH/ADP regulatory site of glutamate dehydrogenase
Glutamate dehydrogenase (GDH) is a target for treating insulin‐related disorders, such as hyperinsulinism hyperammonemia syndrome. Modeling native ligand binding has shown promise in designing GDH inhibitors and activators. Our computational investigation of the nicotinamide adenine diphosphate hydr...
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| Gepubliceerd in: | Protein Sci |
|---|---|
| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
John Wiley & Sons, Inc.
2019
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6863735/ https://ncbi.nlm.nih.gov/pubmed/31610054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3748 |
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