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Expression, purification and characterization of human glutamate dehydrogenase (GDH) allosteric regulatory mutations.

Glutamate dehydrogenase (GDH) catalyses the reversible oxidative deamination of l-glutamate to 2-oxoglutarate in the mitochondrial matrix. In mammals, this enzyme is highly regulated by allosteric effectors. The major allosteric activator and inhibitor are ADP and GTP, respectively; allosteric activ...

詳細記述

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書誌詳細
主要な著者: Fang, Jie, Hsu, Betty Y L, MacMullen, Courtney M, Poncz, Mortimer, Smith, Thomas J, Stanley, Charles A
フォーマット: Artigo
言語:Inglês
出版事項: 2002
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222454/
https://ncbi.nlm.nih.gov/pubmed/11903050
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