Expression, purification and characterization of human glutamate dehydrogenase (GDH) allosteric regulatory mutations.

Glutamate dehydrogenase (GDH) catalyses the reversible oxidative deamination of l-glutamate to 2-oxoglutarate in the mitochondrial matrix. In mammals, this enzyme is highly regulated by allosteric effectors. The major allosteric activator and inhibitor are ADP and GTP, respectively; allosteric activ...

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Detaylı Bibliyografya
Asıl Yazarlar: Fang, Jie, Hsu, Betty Y L, MacMullen, Courtney M, Poncz, Mortimer, Smith, Thomas J, Stanley, Charles A
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2002
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222454/
https://ncbi.nlm.nih.gov/pubmed/11903050
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