Methocinnamox Produces Long-Lasting Antagonism of the Behavioral Effects of µ-Opioid Receptor Agonists but Not Prolonged Precipitated Withdrawal in Rats

A novel µ-opioid receptor antagonist, methocinnamox (MCAM), attenuates some abuse-related and toxic effects of opioids. This study further characterized the pharmacology of MCAM in separate groups of rats using procedures to examine antinociception, gastrointestinal motility, and withdrawal in morph...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Pharmacol Exp Ther
Main Authors: Gerak, Lisa R., Minervini, Vanessa, Latham, Elizabeth, Ghodrati, Saba, Lillis, Katherine V., Wooden, Jessica, Disney, Alex, Husbands, Stephen M., France, Charles P.
פורמט: Artigo
שפה:Inglês
יצא לאור: The American Society for Pharmacology and Experimental Therapeutics 2019
נושאים:
Behavioral Pharmacology
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6863459/
https://ncbi.nlm.nih.gov/pubmed/31439807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.119.260331
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