GZ-11608, a Vesicular Monoamine Transporter-2 Inhibitor, Decreases the Neurochemical and Behavioral Effects of Methamphetamine

Despite escalating methamphetamine use and high relapse rates, pharmacotherapeutics for methamphetamine use disorders are not available. Our iterative drug discovery program had found that R-N-(1,2-dihydroxypropyl)-2,6-cis-di-(4-methoxyphenethyl)piperidine hydrochloride (GZ-793A), a selective vesicu...

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Dettagli Bibliografici
Pubblicato in:J Pharmacol Exp Ther
Autori principali: Lee, Na-Ra, Zheng, Guangrong, Leggas, Markos, Janganati, Venumadhav, Nickell, Justin R., Crooks, Peter A., Bardo, Michael T., Dwoskin, Linda P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Pharmacology and Experimental Therapeutics 2019
Soggetti:
Neuropharmacology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6863457/
https://ncbi.nlm.nih.gov/pubmed/31413138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.119.258699
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