GZ-11608, a Vesicular Monoamine Transporter-2 Inhibitor, Decreases the Neurochemical and Behavioral Effects of Methamphetamine

Despite escalating methamphetamine use and high relapse rates, pharmacotherapeutics for methamphetamine use disorders are not available. Our iterative drug discovery program had found that R-N-(1,2-dihydroxypropyl)-2,6-cis-di-(4-methoxyphenethyl)piperidine hydrochloride (GZ-793A), a selective vesicu...

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Detalhes bibliográficos
Publicado no:J Pharmacol Exp Ther
Main Authors: Lee, Na-Ra, Zheng, Guangrong, Leggas, Markos, Janganati, Venumadhav, Nickell, Justin R., Crooks, Peter A., Bardo, Michael T., Dwoskin, Linda P.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2019
Assuntos:
Neuropharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6863457/
https://ncbi.nlm.nih.gov/pubmed/31413138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.119.258699
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