GZ-11608, a Vesicular Monoamine Transporter-2 Inhibitor, Decreases the Neurochemical and Behavioral Effects of Methamphetamine

Despite escalating methamphetamine use and high relapse rates, pharmacotherapeutics for methamphetamine use disorders are not available. Our iterative drug discovery program had found that R-N-(1,2-dihydroxypropyl)-2,6-cis-di-(4-methoxyphenethyl)piperidine hydrochloride (GZ-793A), a selective vesicu...

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Bibliografiske detaljer
Udgivet i:J Pharmacol Exp Ther
Main Authors: Lee, Na-Ra, Zheng, Guangrong, Leggas, Markos, Janganati, Venumadhav, Nickell, Justin R., Crooks, Peter A., Bardo, Michael T., Dwoskin, Linda P.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Pharmacology and Experimental Therapeutics 2019
Fag:
Neuropharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6863457/
https://ncbi.nlm.nih.gov/pubmed/31413138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.119.258699
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