Chargement en cours...
1,4-Diphenalkylpiperidines: A new scaffold for the design of potent inhibitors of the vesicular monoamine transporter-2
A series of 1,4-diphenalkylpiperidine analogs were synthesized and evaluated for their affinity and inhibitory potency at the [(3)H]dihydrotetrabenazine (DTBZ) binding site and [(3)H]dopamine (DA) uptake site on the vesicular monoamine transporter-2 (VMAT2). Results revealed that translocation of th...
Enregistré dans:
| Publié dans: | Bioorg Med Chem Lett |
|---|---|
| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2016
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4946565/ https://ncbi.nlm.nih.gov/pubmed/27212067 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2016.05.025 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|