Human mesenchymal stromal cells broadly modulate high glucose-induced inflammatory responses of renal proximal tubular cell monolayers

BACKGROUND: Renal proximal tubular epithelial cells (RPTEC) are dysfunctional in diabetic kidney disease (DKD). Mesenchymal stromal cells (MSC) may modulate DKD pathogenesis through anti-inflammatory mediators. This study aimed to investigate the pro-inflammatory effect of extended exposure to high...

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Bibliografiske detaljer
Udgivet i:Stem Cell Res Ther
Main Authors: Islam, Md Nahidul, Griffin, Tomás P., Sander, Elizabeth, Rocks, Stephanie, Qazi, Junaid, Cabral, Joana, McCaul, Jasmin, McMorrow, Tara, Griffin, Matthew D.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6862760/
https://ncbi.nlm.nih.gov/pubmed/31744554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-019-1424-5
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