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Fenofibrate increases very-long-chain sphingolipids and improves blood glucose homeostasis in NOD mice
AIMS/HYPOTHESIS: Sphingolipid metabolism regulates beta cell biology and inflammation and is abnormal at the onset of type 1 diabetes. Fenofibrate, a regulator of sphingolipid metabolism, is known to prevent diabetes in NOD mice. Here, we aimed to investigate the effects of fenofibrate on the pancre...
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| Опубликовано в: : | Diabetologia |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Springer Berlin Heidelberg
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6861358/ https://ncbi.nlm.nih.gov/pubmed/31410530 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-019-04973-z |
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