L-serine supplementation lowers diabetes incidence and improves blood glucose homeostasis in NOD mice

Sphingolipids are a diverse group of lipids with important roles in beta-cell biology regulating insulin folding and controlling apoptosis. Sphingolipid biosynthesis begins with the condensation of L-serine and palmitoyl-CoA. Here we tested the effect of L-serine supplementation on autoimmune diabet...

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Publicat a:PLoS One
Autors principals: Holm, Laurits J., Haupt-Jorgensen, Martin, Larsen, Jesper, Giacobini, Jano D., Bilgin, Mesut, Buschard, Karsten
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5854405/
https://ncbi.nlm.nih.gov/pubmed/29543915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0194414
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