Circulating Lymphangioleiomyomatosis Tumor Cells With Loss of Heterozygosity in the TSC2 Gene Show Increased Aldehyde Dehydrogenase Activity

BACKGROUND: Lymphangioleiomyomatosis (LAM) is a destructive metastasizing neoplasm of the lung characterized by proliferation of LAM cells in specialized lung nodules. LAM cells are characterized by expression of the prometastatic and cancer-initiating hyaluronan receptor CD44v6, and loss of heteroz...

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Detalhes bibliográficos
Publicado no:Chest
Main Authors: Pacheco-Rodríguez, Gustavo, Steagall, Wendy K., Samsel, Leigh, Dagur, Pradeep K., McCoy, J. Philip, Tunc, Ilker, Pirooznia, Mehdi, Wang, Ji-An, Darling, Thomas N., Moss, Joel
Formato: Artigo
Idioma:Inglês
Publicado em: American College of Chest Physicians 2019
Assuntos:
Diffuse Lung Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6859254/
https://ncbi.nlm.nih.gov/pubmed/31034819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chest.2019.03.040
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