Phenotypic Characterization of Disseminated Cells with TSC2 Loss of Heterozygosity in Patients with Lymphangioleiomyomatosis

Rationale: Lymphangioleiomyomatosis (LAM), occurring sporadically (S-LAM) or in patients with tuberous sclerosis complex (TSC), results from abnormal proliferation of LAM cells exhibiting mutations or loss of heterozygosity (LOH) of the TSC genes, TSC1 or TSC2. Objectives: To identify molecular mark...

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Detalhes bibliográficos
Main Authors: Cai, Xiong, Pacheco-Rodriguez, Gustavo, Fan, Qing-Yuan, Haughey, Mary, Samsel, Leigh, El-Chemaly, Souheil, Wu, Hai-Ping, McCoy, J. Philip, Steagall, Wendy K., Lin, Jing-Ping, Darling, Thomas N., Moss, Joel
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2010
Assuntos:
F. Interstitial Lung Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3029931/
https://ncbi.nlm.nih.gov/pubmed/20639436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201003-0489OC
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