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P-Glycoprotein Inhibition Sensitizes Human Breast Cancer Cells to Proteasome Inhibitors

Although effective for the treatment of hematological malignancies, the FDA approved proteasome inhibitors bortezomib and carfilzomib have limited efficacy in solid tumors including triple negative breast cancer (TNBC). Chemotherapy is the only option for treating TNBC due to the absence of specific...

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Опубликовано в: :J Cell Biochem
Главные авторы: Deshmukh, Rahul R., Kim, Seongho, Elghoul, Yasmine, Dou, Q. Ping
Формат: Artigo
Язык:Inglês
Опубликовано: 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6858998/
https://ncbi.nlm.nih.gov/pubmed/27813130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.25783
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