Tumor Necrosis Factor-α Sensitizes Breast Cancer Cells to Natural Products with Proteasome-Inhibitory Activity Leading to Apoptosis

The inflammatory microenvironment plays an important role in the process of tumor development. Tumor necrosis factor-α (TNF-α), a key pro-inflammatory cytokine, has a significant role in this process. Natural medicinal products such as Withaferin A (WA) and Celastrol (Cel) have shown anti-cancer and...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lu, Li, Shi, Wenli, Deshmukh, Rahul R., Long, Jie, Cheng, Xiaoli, Ji, Weidong, Zeng, Guohua, Chen, Xianliang, Zhang, Yajie, Dou, Q. Ping
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4242672/
https://ncbi.nlm.nih.gov/pubmed/25419573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113783
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