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Involvement of ALAD-20S Proteasome Complexes in Ubiquitination and Acetylation of Proteasomal α2 Subunits

The ubiquitin-proteasome pathway has gained attention as a potential chemotherapeutic target, owing to its importance in the maintenance of protein homeostasis and the observation that cancer cells are more dependent on this pathway than normal cells. Additionally, inhibition of histone deacetylases...

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Bibliographische Detailangaben
Veröffentlicht in:J Cell Biochem
Hauptverfasser: Schmitt, Sara M., Neslund-Dudas, Christine, Shen, Min, Cui, Cindy, Mitra, Bharati, Dou, Q. Ping
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4683122/
https://ncbi.nlm.nih.gov/pubmed/26084403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.25259
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