Prodrugs of Fluoro-Substituted Benzoates of EGC as Tumor Cellular Proteasome Inhibitors and Apoptosis Inducers

The most potent catechin in green tea is (-)-epigallocatechin-3-gallate [(-)-EGCG], which, however, is unstable under physiological conditions. To discover more stable and more potent polyphenol proteasome inhibitors, we synthesized several novel fluoro-substituted (-)-EGCG analogs, named F-EGCG ana...

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Main Authors: Yu, Zhiyong, Qin, Xu Long, Gu, Yan Yan, Chen, Di, Cui, Qiuzhi Cindy, Jiang, Tao, Wan, Sheng Biao, Dou, Q. Ping
Formato: Artigo
Idioma:Inglês
Publicado: Molecular Diversity Preservation International (MDPI) 2008
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2658777/
https://ncbi.nlm.nih.gov/pubmed/19325839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms9060951
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