Clioquinol and pyrrolidine dithiocarbamate complex with copper to form proteasome inhibitors and apoptosis inducers in human breast cancer cells

INTRODUCTION: A physiological feature of many tumor tissues and cells is the tendency to accumulate high concentrations of copper. While the precise role of copper in tumors is cryptic, copper, but not other trace metals, is required for angiogenesis. We have recently reported that organic copper-co...

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Detalhes bibliográficos
Main Authors: Daniel, Kenyon G, Chen, Di, Orlu, Shirley, Cui, Qiuzhi Cindy, Miller, Fred R, Dou, Q Ping
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1410741/
https://ncbi.nlm.nih.gov/pubmed/16280039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr1322
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