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P-Glycoprotein Inhibition Sensitizes Human Breast Cancer Cells to Proteasome Inhibitors

Although effective for the treatment of hematological malignancies, the FDA approved proteasome inhibitors bortezomib and carfilzomib have limited efficacy in solid tumors including triple negative breast cancer (TNBC). Chemotherapy is the only option for treating TNBC due to the absence of specific...

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Detalhes bibliográficos
Publicado no:J Cell Biochem
Main Authors: Deshmukh, Rahul R., Kim, Seongho, Elghoul, Yasmine, Dou, Q. Ping
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6858998/
https://ncbi.nlm.nih.gov/pubmed/27813130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.25783
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