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Sensitizing human multiple myeloma cells to the proteasome inhibitor bortezomib by novel curcumin analogs

The proteasome plays a vital role in the degradation of proteins involved in several pathways including the cell cycle, cellular proliferation and apoptosis and is a validated target in cancer treatment. Bortezomib (Velcade(®), PS-341) is the first US FDA approved proteasome inhibitor anticancer dru...

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Bibliographic Details
Main Authors: MUJTABA, TASKEEN, KANWAR, JYOTI, WAN, SHENG BIAO, CHAN, TAK HANG, DOU, Q. PING
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307794/
https://ncbi.nlm.nih.gov/pubmed/22012631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2011.814
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