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Sensitizing human multiple myeloma cells to the proteasome inhibitor bortezomib by novel curcumin analogs
The proteasome plays a vital role in the degradation of proteins involved in several pathways including the cell cycle, cellular proliferation and apoptosis and is a validated target in cancer treatment. Bortezomib (Velcade(®), PS-341) is the first US FDA approved proteasome inhibitor anticancer dru...
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| Главные авторы: | , , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
D.A. Spandidos
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3307794/ https://ncbi.nlm.nih.gov/pubmed/22012631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2011.814 |
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