Načítá se...
The impact of nonsense-mediated mRNA decay on genetic disease, gene editing and cancer immunotherapy
Premature termination codons (PTCs) can result in the production of truncated proteins or the degradation of mRNAs by nonsense-mediated mRNA decay (NMD). Which of these outcomes occurs can alter the effect of a mutation, with the engagement of NMD depending upon a series of rules. Here, by applying...
Uloženo v:
| Vydáno v: | Nat Genet |
|---|---|
| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2019
|
| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6858879/ https://ncbi.nlm.nih.gov/pubmed/31659324 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-019-0517-5 |
| Tagy: |
Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!
|