An atlas of cortical circular RNA expression in Alzheimer disease brains demonstrates clinical and pathological associations

We generated parietal cortex RNA-seq data from individuals with and without Alzheimer disease (AD; n(control) = 13; n(AD) = 83) from the Knight-ADRC. Using this and an independent (MSBB) AD RNA-seq dataset, we quantified cortical circular RNA (circRNA) expression in the context of AD. We identified...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Nat Neurosci
Hlavní autoři: Dube, Umber, Del-Aguila, Jorge L, Li, Zeran, Budde, John P, Jiang, Shan, Hsu, Simon, Ibanez, Laura, Fernandez, Maria Victoria, Farias, Fabiana, Norton, Joanne, Gentsch, Jen, Wang, Fengxian, Salloway, Stephen, Masters, Colin L, Lee, Jae-Hong, Graff-Radford, Neill R, Chhatwal, Jasmeer P, Bateman, Randall J, Morris, John C, Karch, Celeste M, Harari, Oscar, Cruchaga, Carlos
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6858549/
https://ncbi.nlm.nih.gov/pubmed/31591557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41593-019-0501-5
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky