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A selective and rapid cell-permeable inhibitor of human caspase-3

The individual roles and overlapping functionalities the twelve human caspases have during apoptosis and other cellular processes remain poorly resolved primarily due to a lack of chemical tools. Here we present a new selective caspase-3 inhibitor, termed Ac-ATS010-KE, with rapid and irreversible bi...

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Detalhes bibliográficos
Publicado no:ACS Chem Biol
Main Authors: Solania, Angelo, González-Páez, Gonzalo E., Wolan, Dennis W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6858491/
https://ncbi.nlm.nih.gov/pubmed/31334631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.9b00564
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