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Fibrils Colocalize Caspase-3 with Procaspase-3 to Foster Maturation

Most proteases are expressed as inactive precursors, or zymogens, that become activated by limited proteolysis. We previously identified a small molecule, termed 1541, that dramatically promotes the maturation of the zymogen, procaspase-3, to its mature form, caspase-3. Surprisingly, compound 1541 s...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Zorn, Julie A., Wolan, Dennis W., Agard, Nicholas J., Wells, James A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3460474/
https://ncbi.nlm.nih.gov/pubmed/22872644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.386128
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