Clinical Implication of Dosimetry of Computed Tomography- and Fluoroscopy-Guided Intrathecal Therapy With Nusinersen in Adult Patients With Spinal Muscular Atrophy

Background: Spinal muscular atrophy (SMA) is a genetic disorder that leads to progressive tetraparesis. Nusinersen is the first approved drug for the treatment of SMA and is administered via intrathecal injections. Neuromyopathic scoliosis and spondylodesis can impede lumbar punctures, thus necessit...

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Enregistré dans:
Détails bibliographiques
Publié dans:Front Neurol
Auteurs principaux: Kizina, Kathrin, Stolte, Benjamin, Totzeck, Andreas, Bolz, Saskia, Fleischer, Michael, Mönninghoff, Christoph, Guberina, Nika, Oldenburg, Denise, Forsting, Michael, Kleinschnitz, Christoph, Hagenacker, Tim
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2019
Sujets:
Neurology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6856637/
https://ncbi.nlm.nih.gov/pubmed/31787921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2019.01166
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