Clinical Implication of Dosimetry of Computed Tomography- and Fluoroscopy-Guided Intrathecal Therapy With Nusinersen in Adult Patients With Spinal Muscular Atrophy

Background: Spinal muscular atrophy (SMA) is a genetic disorder that leads to progressive tetraparesis. Nusinersen is the first approved drug for the treatment of SMA and is administered via intrathecal injections. Neuromyopathic scoliosis and spondylodesis can impede lumbar punctures, thus necessit...

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Bibliografski detalji
Izdano u:Front Neurol
Glavni autori: Kizina, Kathrin, Stolte, Benjamin, Totzeck, Andreas, Bolz, Saskia, Fleischer, Michael, Mönninghoff, Christoph, Guberina, Nika, Oldenburg, Denise, Forsting, Michael, Kleinschnitz, Christoph, Hagenacker, Tim
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2019
Teme:
Neurology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6856637/
https://ncbi.nlm.nih.gov/pubmed/31787921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2019.01166
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