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Neurofilament Heavy Chain and Tau Protein Are Not Elevated in Cerebrospinal Fluid of Adult Patients with Spinal Muscular Atrophy during Loading with Nusinersen

Nusinersen is the first approved drug for the treatment of spinal muscular atrophy (SMA). Treatment of SMA with nusinersen is based on a fixed dosing regimen. For other motoneuron diseases, such as amyotrophic lateral sclerosis (ALS), biomarkers are available for clinical diagnostics; however, no su...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Totzeck, Andreas, Stolte, Benjamin, Kizina, Kathrin, Bolz, Saskia, Schlag, Melina, Thimm, Andreas, Kleinschnitz, Christoph, Hagenacker, Tim
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6862027/
https://ncbi.nlm.nih.gov/pubmed/31671515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20215397
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