Llwytho...

Unc93b1 recruits Syntenin-1 to dampen TLR7 signaling and prevent autoimmunity

At least two members of the Toll-like receptor (TLR) family, TLR7 and TLR9, can recognize self-RNA or DNA, respectively. Despite the structural and functional similarities between these receptors, their contribution to autoimmune diseases such as systemic lupus erythematosus (SLE) can be quite diffe...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nature
Prif Awduron: Majer, Olivia, Liu, Bo, Kreuk, Lieselotte SM, Krogan, Nevan, Barton, Gregory M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6856441/
https://ncbi.nlm.nih.gov/pubmed/31546246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1612-6
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!