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Unc93b1 recruits Syntenin-1 to dampen TLR7 signaling and prevent autoimmunity
At least two members of the Toll-like receptor (TLR) family, TLR7 and TLR9, can recognize self-RNA or DNA, respectively. Despite the structural and functional similarities between these receptors, their contribution to autoimmune diseases such as systemic lupus erythematosus (SLE) can be quite diffe...
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| Publicado no: | Nature |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6856441/ https://ncbi.nlm.nih.gov/pubmed/31546246 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1612-6 |
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