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UNC93B1 Physically Associates with Human TLR8 and Regulates TLR8-Mediated Signaling

Toll-like receptors (TLRs) 3, 7, 8, and 9 are localized to intracellular compartments where they encounter foreign or self nucleic acids and activate innate and adaptive immune responses. The endoplasmic reticulum (ER)-resident membrane protein, UNC93B1, is essential for intracellular trafficking an...

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Detalhes bibliográficos
Main Authors: Itoh, Hiroki, Tatematsu, Megumi, Watanabe, Ayako, Iwano, Katsunori, Funami, Kenji, Seya, Tsukasa, Matsumoto, Misako
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3229609/
https://ncbi.nlm.nih.gov/pubmed/22164301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028500
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