Toll-Like Receptor 3 Signal in Dendritic Cells Benefits Cancer Immunotherapy

Pattern recognition receptors (PRRs) play a crucial role in the innate immune system and contribute to host defense against microbial infection. PRR-mediated antimicrobial signals provide robust type-I IFN/cytokine production and trigger inflammation, thereby affecting tumor progression and autoimmu...

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Bibliografische gegevens
Hoofdauteurs: Misako Matsumoto, Yohei Takeda, Megumi Tatematsu, Tsukasa Seya
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2017-12-01
Reeks:Frontiers in Immunology
Onderwerpen:
adjuvant
cancer immunotherapy
checkpoint inhibitors
cross-priming
dendritic cells
double-stranded RNA
Online toegang:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01897/full
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