Adjuvant for vaccine immunotherapy of cancer – focusing on Toll‐like receptor 2 and 3 agonists for safely enhancing antitumor immunity

Immune‐enhancing adjuvants usually targets antigen (Ag)‐presenting cells to tune up cellular and humoral immunity. CD141(+) dendritic cells (DC) represent the professional Ag‐presenting cells in humans. In response to microbial pattern molecules, these DCs upgrade the maturation stage sufficient to...

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Bibliographic Details
Published in:Cancer Sci
Main Authors: Seya, Tsukasa, Shime, Hiroaki, Takeda, Yohei, Tatematsu, Megumi, Takashima, Ken, Matsumoto, Misako
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2015
Subjects:
Review Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4714660/
https://ncbi.nlm.nih.gov/pubmed/26395101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12824
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