Anti-oxidative Amino Acid L-ergothioneine Modulates the Tumor Microenvironment to Facilitate Adjuvant Vaccine Immunotherapy

Cancer vaccines consist of a tumor-associated antigen (TAA) and adjuvant. These vaccines induce and activate proliferation of TAA-specific cytotoxic T lymphocytes (CTLs), suppressing tumor growth. The therapeutic efficacy of TAA-specific CTLs depends on the properties of tumor microenvironment. The...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Yoshida, Sumito, Shime, Hiroaki, Matsumoto, Misako, Kasahara, Masanori, Seya, Tsukasa
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6458301/
https://ncbi.nlm.nih.gov/pubmed/31019508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00671
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