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Drug-Selective Anesthetic Insensitivity of Zebrafish Lacking γ-Aminobutyric Acid Type A Receptor β3 Subunits
BACKGROUND: Transgenic mouse studies suggest that γ-aminobutyric acid type A (GABA(A)) receptors containing β3 subunits mediate important effects of etomidate, propofol, and pentobarbital. Zebrafish, recently introduced for rapid discovery and characterization of sedative-hypnotics, could also accel...
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| Publicado no: | Anesthesiology |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6856434/ https://ncbi.nlm.nih.gov/pubmed/31567362 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0000000000002963 |
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