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Ubiquitylation and endocytosis of the human LAT1/SLC7A5 amino acid transporter

The human L-type amino acid transporter 1 (LAT1), also known as SLC7A5, catalyzes the transport of large neutral amino acids across the plasma membrane. As the main transporter of several essential amino acids, notably leucine, LAT1 plays an important role in mTORC1 activation. Furthermore, it is ov...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Barthelemy, Céline, André, Bruno
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6856120/
https://ncbi.nlm.nih.gov/pubmed/31728037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-53065-w
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