The Human SLC7A5 (LAT1): The Intriguing Histidine/Large Neutral Amino Acid Transporter and Its Relevance to Human Health

SLC7A5, known as LAT1, belongs to the APC superfamily and forms a heterodimeric amino acid transporter interacting with the glycoprotein CD98 (SLC3A2) through a conserved disulfide. The complex is responsible for uptake of essential amino acids in crucial body districts such as placenta and blood br...

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Bibliographic Details
Published in:Front Chem
Main Authors: Scalise, Mariafrancesca, Galluccio, Michele, Console, Lara, Pochini, Lorena, Indiveri, Cesare
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2018
Subjects:
Chemistry
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6023973/
https://ncbi.nlm.nih.gov/pubmed/29988369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2018.00243
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