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Substrate-Induced Ubiquitylation and Endocytosis of Yeast Amino Acid Permeases

Many plasma membrane transporters are downregulated by ubiquitylation, endocytosis, and delivery to the lysosome in response to various stimuli. We report here that two amino acid transporters of Saccharomyces cerevisiae, the general amino acid permease (Gap1) and the arginine-specific permease (Can...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Ghaddar, Kassem, Merhi, Ahmad, Saliba, Elie, Krammer, Eva-Maria, Prévost, Martine, André, Bruno
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248734/
https://ncbi.nlm.nih.gov/pubmed/25266656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00699-14
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