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Substrate-Induced Ubiquitylation and Endocytosis of Yeast Amino Acid Permeases

Many plasma membrane transporters are downregulated by ubiquitylation, endocytosis, and delivery to the lysosome in response to various stimuli. We report here that two amino acid transporters of Saccharomyces cerevisiae, the general amino acid permease (Gap1) and the arginine-specific permease (Can...

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Veröffentlicht in:Mol Cell Biol
Hauptverfasser: Ghaddar, Kassem, Merhi, Ahmad, Saliba, Elie, Krammer, Eva-Maria, Prévost, Martine, André, Bruno
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248734/
https://ncbi.nlm.nih.gov/pubmed/25266656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00699-14
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