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Transition of yeast Can1 transporter to the inward-facing state unveils an α-arrestin target sequence promoting its ubiquitylation and endocytosis

Substrate-transport–elicited endocytosis is a common control mechanism of membrane transporters avoiding excess uptake of external compounds, though poorly understood at the molecular level. In yeast, endocytosis of transporters is triggered by their ubiquitylation mediated by the Rsp5 ubiquitin-lig...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Biol Cell
Hauptverfasser: Gournas, Christos, Saliba, Elie, Krammer, Eva-Maria, Barthelemy, Céline, Prévost, Martine, André, Bruno
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5638585/
https://ncbi.nlm.nih.gov/pubmed/28814503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-02-0104
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