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Yeast α-arrestin Art2 is the key regulator of ubiquitylation-dependent endocytosis of plasma membrane vitamin B1 transporters

Endocytosis of membrane proteins in yeast requires α-arrestin-mediated ubiquitylation by the ubiquitin ligase Rsp5. Yet, the diversity of α-arrestin targets studied is restricted to a small subset of plasma membrane (PM) proteins. Here, we performed quantitative proteomics to identify new targets of...

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Publicat a:PLoS Biol
Autors principals: Savocco, Jérôme, Nootens, Sylvain, Afokpa, Wilhelmine, Bausart, Mathilde, Chen, Xiaoqian, Villers, Jennifer, Renard, Henri-François, Prévost, Martine, Wattiez, Ruddy, Morsomme, Pierre
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6837554/
https://ncbi.nlm.nih.gov/pubmed/31658248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000512
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