Importance of thorough tissue and cellular level characterization of targeted drugs in the evaluation of pharmacodynamic effects

Targeted nanoparticle delivery is a promising strategy for increasing efficacy and limiting side effects of therapeutics. When designing a targeted liposomal formulation, the in vivo biodistribution of the particles must be characterized to determine the value of the targeting approach. Peroxisome p...

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Publicado en:PLoS One
Autores principales: Bauknight, Dustin K., Osinski, Victoria, Dasa, Siva Sai Krishna, Nguyen, Anh T., Marshall, Melissa A., Hartman, Julia, Harms, Matthew, O’Mahony, Gavin, Boucher, Jeremie, Klibanov, Alexander L., McNamara, Coleen A., Kelly, Kimberly A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6855449/
https://ncbi.nlm.nih.gov/pubmed/31725756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0224917
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