Importance of thorough tissue and cellular level characterization of targeted drugs in the evaluation of pharmacodynamic effects

Targeted nanoparticle delivery is a promising strategy for increasing efficacy and limiting side effects of therapeutics. When designing a targeted liposomal formulation, the in vivo biodistribution of the particles must be characterized to determine the value of the targeting approach. Peroxisome p...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Bauknight, Dustin K., Osinski, Victoria, Dasa, Siva Sai Krishna, Nguyen, Anh T., Marshall, Melissa A., Hartman, Julia, Harms, Matthew, O’Mahony, Gavin, Boucher, Jeremie, Klibanov, Alexander L., McNamara, Coleen A., Kelly, Kimberly A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6855449/
https://ncbi.nlm.nih.gov/pubmed/31725756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0224917
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