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Evaluation of pharmacokinetic and pharmacodynamic profiles of liposomes for the cell type-specific delivery of small molecule drugs

Liposome-based drug formulations represent an exciting avenue of research as they increase efficacy to toxicity ratios. Current formulations rely on passive accumulation to the disease site where drug is taken up by the cells. Ligand mediated targeting increases the net accumulation of liposomes, ho...

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Detalhes bibliográficos
Publicado no:Nanomedicine
Main Authors: Dasa, Siva Sai Krishna, Suzuki, Ryo, Mugler, Emily, Chen, Lanlin, Jansson-Löfmark, Rasmus, Michaëlsson, Erik, Lindfors, Lennart, Klibanov, Alexander L., French, Brent A., Kelly, Kimberly A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5673558/
https://ncbi.nlm.nih.gov/pubmed/28754465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2017.07.005
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