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An automated data-driven pipeline for improving heterologous enzyme expression
Enzymes are the ultimate entities responsible for chemical transformations in natural and engineered biosynthetic pathways. However, many natural enzymes suffer from suboptimal functional expression due to poor intrinsic protein stability. Further, stability enhancing mutations often come at the cos...
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| Pubblicato in: | ACS Synth Biol |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6855305/ https://ncbi.nlm.nih.gov/pubmed/30721031 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acssynbio.8b00486 |
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