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Neurons Expressing Pathological Tau Protein Trigger Dramatic Changes in Microglial Morphology and Dynamics

Microglial cells, the resident macrophages of the brain, are important players in the pathological process of numerous neurodegenerative disorders, including tauopathies, a heterogeneous class of diseases characterized by intraneuronal Tau aggregates. However, microglia response in Tau pathologies r...

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Détails bibliographiques
Publié dans:Front Neurosci
Auteurs principaux: Hassan-Abdi, Rahma, Brenet, Alexandre, Bennis, Mohamed, Yanicostas, Constantin, Soussi-Yanicostas, Nadia
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6855094/
https://ncbi.nlm.nih.gov/pubmed/31787873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2019.01199
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