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Defective Excitatory/Inhibitory Synaptic Balance and Increased Neuron Apoptosis in a Zebrafish Model of Dravet Syndrome

Dravet syndrome is a type of severe childhood epilepsy that responds poorly to current anti-epileptic drugs. In recent years, zebrafish disease models with Scn1Lab sodium channel deficiency have been generated to seek novel anti-epileptic drug candidates, some of which are currently undergoing clini...

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發表在:Cells
Main Authors: Brenet, Alexandre, Hassan-Abdi, Rahma, Somkhit, Julie, Yanicostas, Constantin, Soussi-Yanicostas, Nadia
格式: Artigo
語言:Inglês
出版: MDPI 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6829503/
https://ncbi.nlm.nih.gov/pubmed/31590334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8101199
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