Organophosphorus diisopropylfluorophosphate (DFP) intoxication in zebrafish larvae causes behavioral defects, neuronal hyperexcitation and neuronal death

With millions of intoxications each year and over 200,000 deaths, organophosphorus (OP) compounds are an important public health issue worldwide. OP poisoning induces cholinergic syndrome, with respiratory distress, hypertension, and neuron damage that may lead to epileptic seizures and permanent co...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Brenet, Alexandre, Somkhit, Julie, Hassan-Abdi, Rahma, Yanicostas, Constantin, Romain, Christiane, Bar, Olivier, Igert, Alexandre, Saurat, Dominique, Taudon, Nicolas, Dal-Bo, Gregory, Nachon, Florian, Dupuis, Nina, Soussi-Yanicostas, Nadia
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7645799/
https://ncbi.nlm.nih.gov/pubmed/33154418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76056-8
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