Endotoxin Engages Mitochondrial Quality Control via an iNOS-Reactive Oxygen Species Signaling Pathway in Hepatocytes

BACKGROUND: Organ injury and dysfunction in sepsis accounts for significant morbidity and mortality. Adaptive cellular responses in the setting of sepsis prevent injury and allow for organ recovery. We and others have shown that part of the adaptive response includes regulation of cellular respirati...

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Bibliografiske detaljer
Udgivet i:Oxid Med Cell Longev
Main Authors: Cyr, Anthony, Chambers, Lauran, Waltz, Paul K., Whelan, Sean P., Kohut, Lauryn, Carchman, Evie, Dyer, Mitchell, Luciano, Jason, Kautza, Benjamin, Gomez, Hernando D., Otterbein, Leo E., Rosengart, Matthew R., Shiva, Sruti, Zuckerbraun, Brian S.
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6854992/
https://ncbi.nlm.nih.gov/pubmed/31772705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/4745067
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