Endotoxin Engages Mitochondrial Quality Control via an iNOS-Reactive Oxygen Species Signaling Pathway in Hepatocytes

BACKGROUND: Organ injury and dysfunction in sepsis accounts for significant morbidity and mortality. Adaptive cellular responses in the setting of sepsis prevent injury and allow for organ recovery. We and others have shown that part of the adaptive response includes regulation of cellular respirati...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oxid Med Cell Longev
Main Authors: Cyr, Anthony, Chambers, Lauran, Waltz, Paul K., Whelan, Sean P., Kohut, Lauryn, Carchman, Evie, Dyer, Mitchell, Luciano, Jason, Kautza, Benjamin, Gomez, Hernando D., Otterbein, Leo E., Rosengart, Matthew R., Shiva, Sruti, Zuckerbraun, Brian S.
Format: Artigo
Jezik:Inglês
Izdano: Hindawi 2019
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6854992/
https://ncbi.nlm.nih.gov/pubmed/31772705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/4745067
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