Endotoxin Engages Mitochondrial Quality Control via an iNOS-Reactive Oxygen Species Signaling Pathway in Hepatocytes

BACKGROUND: Organ injury and dysfunction in sepsis accounts for significant morbidity and mortality. Adaptive cellular responses in the setting of sepsis prevent injury and allow for organ recovery. We and others have shown that part of the adaptive response includes regulation of cellular respirati...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Cyr, Anthony, Chambers, Lauran, Waltz, Paul K., Whelan, Sean P., Kohut, Lauryn, Carchman, Evie, Dyer, Mitchell, Luciano, Jason, Kautza, Benjamin, Gomez, Hernando D., Otterbein, Leo E., Rosengart, Matthew R., Shiva, Sruti, Zuckerbraun, Brian S.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6854992/
https://ncbi.nlm.nih.gov/pubmed/31772705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/4745067
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